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& S.R.) assessed the retrieved articles separately to determine their eligibility

This study reports that mitochondrial ROS activate AMPK, which reciprocally limits mitochondrial ROS production via a PGC-1-dependent antioxidant response

A power analysis ( = 0.05 and power = 0.90), based on data where a difference would be significant if the weight loss were 1 kg more than that in CT group with an expected standard deviation of 0.75, indicated that 13 patients would be needed in each group to detect significant difference [18]