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Similarly, a prior study has shown that MB is more toxic in tumor cell lines, presenting EC 50 20,000 folds higher in normal PBMCs compared to tumor cell lines ( 50 of 11 M (3,530 g/mL) in PBMCs, only a slight reduction in cell viability was found at 20 M

Nonetheless, migraine disorder remains a commonly underdiagnosed and undertreated condition (Lipton 2011

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however, the rates for these components are not added or combined to obtain the overall score as they are not mutually exclusive