glutathione deficiency and ms in multiple sclerosis: More than just an antioxidant? Is glutathione beneficial for MS

(2022) showed that Smad 2/3 and stratifin proteins play a detrimental role in CP-induced AKI by inducing necroptosis and necroinflammation, and interestingly, targeting these proteins suppressed the necroptosis signaling and thereby alleviating AKI

PMID 398617

Use of the P2X7R antagonist Brilliant Blue G (BBG) prevented NLRP3 inflammasome activation and subsequent release of interleukin (IL)-1 and IL-18, thereby reducing FMS symptoms ( 5.4 T lymphoid cells As a typical representative population of adaptive immune cells, T cells play an important role in NPP induction, and numerous studies have reported associations between T cells and NPP

doi: 10.1016/j.dib.2021.107507