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Taken together, these studies indicate that lactic acidosis plays multiple roles in modulating metabolic behaviors of cancer cells

Jakobsson PJ, Morgenstern R, Mancini J, et al

Although the oxidative phosphorylation pathway can produce energy in times of stress to aid in the survival of astrocytes and neurons, other pathways have also been found to be capable of sustaining astrocyte survival in the event of mitochondrial inhibition (San Martin et al., 2017)