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Description

Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model

NO is an active molecule produced by the nitric oxide synthase (NOS) protein family, which directly binds and inactivates iron-containing enzymes [48] or reacts with superoxide anion radical O2 to form a highly active peroxy sulfoxide Nitrates (ooo-), which can attack membrane lipids and proteins of the pathogens, especially protein thiols [49]

This study was supported by the Science and Technology Research Project of Henan Province (NO 252102311048) and Henan provincial Medical Science and Technology Research Project (NO LHGJ20240415)