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Furthermore, it remains a critical, testable hypothesis whether ARID1A loss, common in EAOC, alters BDNF promoter accessibility, thereby enhancing ER or AP-1 tethering

Other types of epithelial cells localised within the intestinal crypts are the Lgr5+ ISCs, which ensure epithelial repair and self-renewal

Furthermore, clinical studies have demonstrated rapid recovery in patients with cholera after oral administration of resistant starch, a butyrate precursor (Canani et al., 2011)