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Currently, a series of phase 3 clinical trials, under the name of REDEFINE Program, are underway [13]

*Correspondence: Weina Li, [email protected] Meng Li, [email protected] These authors have contributed equally to this work This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Technological advances have enabled researchers to study spine dynamics in vivo during development as well as under various physiological and pathological conditions

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