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Research has demonstrated that GA modulates the AMPK/SREBP/ACC and IRs-1/Akt signaling pathways, which are pivotal in cellular metabolism, and it also suppresses liver inflammation by targeting the IKK/i-B/NF-B signaling pathway, a key mediator of inflammatory responses ( Previous studies on the mechanism of action of GA on NAFLD were based on pharmacological methods

Other supplements St Johns-wort For patients not already on an SSRI or other medication that effects the serotonin system, St Johns-wort can be a good supplement to try during the luteal phase

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