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Additionally, its high cost, ethical concerns, and the complexity of personalized treatment continue to limit widespread clinical application

A point of interest however, is that the common mutations in the MMR genes that were identified in all four individuals tested, are likely to be LS predisposing gene mutations

Eseberri I, Lasa A, Churruca I, Portillo MP (2013) Resveratrol metabolites modify adipokine expression and secretion in 3T3-L1 pre-adipocytes and mature adipocytes