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Declercq 2013

Structural irregularities: Increased mitochondrial fragmentation and impaired mitophagy, the process responsible for removing damaged organelles (109, 305)

Larger IVs can take between 60 -180 minutes depending on the doses and volume used

Moreover, cells lacking FSP1 expression have increased sensitivity to ferroptosis inducers, including the GPX4 inhibitor ML162 and the system x c - inhibitor erastin [15, 16]