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doi: 10.1186/s40425-017-0268-8 140 BorghaeiHPaz-AresLHornLSpigelDRSteinsMReadyNEet al

Recently, KIO-101 ophthalmic solution, a topical DHODH inhibitor, has been shown to be safe and effective at reducing conjunctival hyperemia at low and medium doses over a 12-day period in patients with herpesvirus (HV) infection and conjunctival hyperemia (57)

This approach enhanced APC activation in cervical lymph nodes and significantly improved SARS-CoV-2-specific IgG and IgA antibody production, supporting both systemic and mucosal immunity