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BBB impairment and edema are very early disease processes To determine the temporal progression of BBB impairment, we simultaneously assessed the degree of BBB permeability and vasogenic edema after 3 days to 5 weeks of cuprizone administration (Fig

From our results, we observed that GHK-Cu exhibits low potential of inducing skin irritation response in comparison with CuCl 2 and Cu(OAc) 2

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However, CL R being comparable to f u GFR in both the clinical study and the in vitro study should adequately indicate the absence of transporters that substantially contribute to the elimination of pudexacianinium