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This promoted T cell-mediated systemic immunity to exert long-range antitumor effects on tumors and enhance RT efficacy, thereby exhibiting superior antitumor efficacy in a bilateral tumor model and a lung metastatic model of 4T1 breast cancer

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from noncanonical necroptotic cell death

instead, they may represent secondary consequences of improved local intestinal barrier function and reduced translocation of inflammatory mediators into the circulation [70]

[DOI] [PMC free article] [PubMed] [Google Scholar] Wang C-C, Peng H, Wang Zet al