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2015;10(4): e0124648

Additionally, integrating metagenomics with metabolomics to identify key functional bacteria involved in metabolic processes and their metabolites will help elucidate the dialogue mechanism underlying "TCM components-GM-host" interactions

Although not a universal finding, a possible mechanism of resistance in MDS is an increase in carbamoyl-phosphate synthetase (CAD) expression, resulting in increased synthesis of dCTP, which competes with aza-dCTP for incorporation into DNA