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Optimization studies confirmed that ultrasonic irradiation in ethanol offered the best performance, whereas non-polar and aprotic polar solvents were less effective, and polar protic solvents such as isopropanol and methanol led to longer reaction times and lower yields compared to ethanol

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Given that dietary intake is the primary source of Mn, the intestines serve as a major site of Mn regulation (Kippler and Oskarsson, 2024)

Among the two polyunsaturated acylcarnitines, octadecadienyl carnitine (C18:2) was found to be decreased in the patients compared to the controls without generating a statistically significant difference (P = 0.113), whereas the concentration of tetradecadienoylcarnitine (C14:2) of the patients and the healthy controls did not differ