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Moreover, phospho-BCL-XL (Ser62) stabilizes G2 arrest by binding to and co-localizing with Cdk1 (cdc2) in nucleolar structures to avoid rapid nucleolar disassembly associated with mitosis onset, playing an unexpected role in the G2 phase checkpoint downstream of DNA damage distinct from its anti-apoptotic function 22

Under physiological cellular Cu levels, these transporters are found to be located in the TGN where they pump Cu from the cytosol into the lumen of the TGN

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