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Figure 3 After the diagnosis of GSSD, the infant continued to receive l-carnitine to improve her metabolism, oral sodium bicarbonate to correct acidosis, and oral vitamins C and E to prevent oxidative stress

Schematic illustrating the process of xenobiotic metabolism, which encompasses three phases I, II, III (Adopted from [137]) as well as xenobiotic induced oxidative stress and molecular damage

In another study with 118 CRC patient cases, HO-1 expression was significantly elevated in CRC tumor tissues when compared to paired normal non-tumoral and polyps samples

Despite extensive preclinical promise, antioxidant therapies have consistently failed in clinical translation