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Induction of autophagy by spermidine promotes longevity

In contrast, the photomicrographs of the DOX + DAPA group demonstrated the presence of degeneration in a few numbers of the pyramidal cells in the hippocampal CA1 zone

The extract displayed dose- and time-dependent antiproliferative effects on A549 cells, with IC 50 decreasing from 340.63 g/mL at 24 h to 107.08 g/mL at 72 h, indicating enhanced cytotoxicity over time