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One research study that started to turn the tide of my thinking was an extensive analysis of more than 1000 foods and beverages in which coffee came out in the top 6 foods highest in antioxidant-rich coffee on a per serving basis (8)

In this study, we report that a select set of metabolites, such as phosphoenol pyruvate (PEP), glutathione (GSH), 2-hydroxyglutarate (2-HG), and NAD + , display significant differences between the healthy and diseased motor cortex with TDP-43 pathology at a symptomatic stage

At the core of the formulation is Reduced L-Glutathione, widely known as the bodys master antioxidant