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Yasuda H, Furukawa Y, Nishioka K, Sasaki M, Tsukune, Shirane S, Hattori N, Ando M, Komatsu N

Ferroptosis is defined by excessive intracellular iron accumulation due to metabolic imbalance, where Fe 2+ generates a large amount of hydroxyl radicals (OH) through the Fenton reaction (Figure 2)