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This causes DNA damage and formation of ONOO due to excess NO (nitrosative stress) and other free radicals

Of note, in addition to the ER stress response, a specific apoptotic response is also required in some cases, whereas it is not necessary in others

As a novel and effective approach distinct from dietary interventions and probiotic supplementation, FMT directly alters the gut microbiota composition and has been explored for the treatment of various microbiota-related disorders, including Clostridium difficile infection ( Recent evidence suggests that intragastric administration of Blautia wexlerae to a mouse model exposed to high-altitude hypoxia significantly increased arterial oxygen partial pressure, improved pulmonary arterial pressure, right ventricular systolic pressure, and lung injury scores

Linkermann A, Brasen JH, Darding M, Jin MK, Sanz AB, Heller J-O, et al