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However, its noteworthy that in 40-60% of HCC cases, there are no mutations in CTNNB1, Axin1, or Axin2 (65)

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doi: 10.1161/atvbaha.120.314139 52 HamzR.DelangreE.ToluS.MoreauM.JanelN.BailbD.et al

Activation of the AMPA receptor (AMPAR) is necessary to induce membrane depolarization, which is responsible for removing Mg 2+ -mediated inhibition of the NMDAR channel