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HYAL1 deficiency attenuates lipopolysaccharide-triggered renal injury and endothelial glycocalyx breakdown in septic AKI in mice

At t = 0 min and t = 70 min, samples were irradiated with visible light (12.5 mW cm 2 ) for 10 min

This is due to the fact that H 2 O 2 can quickly and readily diffuse through cell membranes, primarily through aquaporins (AQPs) 29,30 , as well as between neighbouring cells through gap junctions hemichannels composed of connexins which facilitate the transfer of molecules 13 kDa large such as ROS between cells to propagate oxidative signals 31