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NNMT inhibition as a therapeutic strategy has been explored in industry pharmaceutical pipelines (including a Pfizer program for non-alcoholic fatty liver disease that was reportedly discontinued in early clinical development), but no NNMT inhibitor has reached regulatory approval to date

Archived from the original on February 20, 2008

& Mimic-Oka, J

There is also a potentially relevant interaction between VEGF and FGF-2, as synergistic action between these two factors has been reported in the literature