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The reaction is carried out epimerization , regulated by the pentose-5-phosphate epimerase enzyme, which converts the ribulose-5-phosphate, a product of the oxidative phase, xylulose-5-phosphate, thereby generating the necessary substrate for controlled by the following reaction transketolase , which acts together with coenzyme Thiamine Pyrophosphate (TPP)

In 2000, a study on the selective D3R agonist 7-OH-DPAT revealed its potential role in reducing rabbit intraocular pressure, marking the first indication of D3Rs involvement in lowering eye pressure (163)

Chaudhry N, Joshi L, Dhamija K, Khwaja GA

Note that m + 9 PC is derived from PE via methylation