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For acute injury models, daily dosing is common for the first 7-14 days, transitioning to less frequent administration as the recovery window progresses

739 In the MCAO/R model of rats, the expression of SLC7A11 is downregulated, accompanied by inhibition of GSH and GPX4, suggesting that the deficiency of xCT in cerebral I/R injury may be the main cause of lipid peroxidation and ferroptosis