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This occurs through the blockade of calcium ion (Ca 2 ) influx and capsaicin-induced cell volume contraction

doi: 10.47391/JPMA.7685

In their excellent review of the association between mitochondrial dysfunction and temporal lobe epilepsy, Waldbaum and Patel remind that the first suggestion of mitochondrial dysfunction in epilepsy arose from the observation that epilepsy is frequent in inherited mitochondrial disorders such as those associated with childhood encephalopathies [175]

J Biosci 27:703714 Koeth RA et al (2013) Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis