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A common functional polymorphism at codons 108 and 158 in the genes coding for SCOMT and MBCOMT (COMT Val 108/158 Met), respectively, has been examined in relationship to a number of neurological disorders involving the noradrenergic or dopaminergic systems, such as schizophrenia (Park et al., 2002) or Parkinson's disease (Kunugi et al., 1997)

Significant body composition changes are generally apparent by months three through five

Proc Nat Acad Sci U S A 100:82588263