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In a recent multi-arm trial by Satapathy et al., participants with T2D in one arm of the trial (n = 20) received 500 mcg/day of methylcobalamin for eight weeks 43

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Changes in mucosal architecture, including the presence of inflammatory infiltrates, were also evaluated

Under physiological conditions, the Nrf2 pathway acts as a primary defense mechanism by inducing antioxidant enzymes such as HO-1, SOD, and catalase