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Although a few studies have been conducted in humans, the results are mixed and ultimately the drug is not approved by the US Food and Drug Administration (FDA)

There are also indications that BPC-157 could modulate vascular endothelial growth factor (VEGF) pathways, which may assist in angiogenesis and remodeling processes

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Given that both diet composition and adiposity can each substantially impact the gut microflora in obese mice 24 , we conducted a secondary endpoint study using animals given the same series of diets to test the hypothesis that NNMTi treatment combined with LD, but not LD alone, shifts the cecal microbiome profile of obese animals to be similar to age-matched LD controls that were never given a high-fat diet