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Specifically, the protein NGAL, in conjunction with iron and metformin, forms complexes that drive neutrophil infiltration into the kidneys, ultimately leading to NETosis and worsening AKI

Trending hs-CRP over time is more useful than a single value

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For instance, curcumin inhibits NFB signaling by preventing IB degradation and subsequent nuclear translocation of NFB subunits, thereby suppressing the expression of proinflammatory cytokines such as TNF, IL1, and IL6 (Fuloria et al