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PloS One

Parameters to monitor Weight Serum electrolytes BUN and creatinine Uric acid Hearing (in high doses) Potassium-sparing diuretics See Table 12-7 for a list of potassium-sparing diuretics, their usual dosage range, and adverse effects associated with these medications

We review your medical history to avoid risk for patients with bleeding disorders, neurological conditions, or allergies

In aged skeletal muscle models, NNMT inhibitor treatment increased proliferating/active muscle stem cells by 60-75% following injury, myofiber cross-sectional area increased 1.8-fold at one week post-injury with high-dose treatment, and peak torque of injured muscle increased by 67% compared to control (p = 0.033), with no untoward systemic toxicity observed in plasma chemistry markers (Neelakantan et al., 2019)