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Studies in various normal and malignant cells suggest that the ligation of this receptor modulates the activation of various intracellular pathways [33,34,35,36,37,38], including PI3K (Phosphatidylinositol-4,5-bisphosphate 3-kinase)-Akt(Protein kinase B)-mTOR (the mechanistic target of rapamycin kinase) [34,37,38], FAK (focal adhesion kinase) [35,36], STAT3 (a signal transducer and activator of transcription 3) [34,38] and ERK (extracellular signal-regulated kinase)1/2 activation [38]

Detox pathways in the liver and skin get a subtle boost

Candida albicans Colonization Modulates Murine Ethanol Consumption and Behavioral Responses Through Elevation of Serum Prostaglandin E(2) and Impact on the Striatal Dopamine System

Lewak S (2011) Metabolic control of embryonic dormancy in apple seed: seven decades of research