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Closer inspection of the MPP lid region reveal two other regions which re-arrange upon PINK1 binding namely, portions of the PRQ-helix, which lies next to the RLY helix, and the short HIQT-helix, which lies next to the PRQ-helix (Fig 4B)

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In animal models, L-theanine appears to have a dose-dependent biphasic effect on NSAID-induced gastric ulcers, delaying healing at higher doses (40 mg/kg), but accelerating healing at lower doses (10 mg/kg) perhaps through the maintenance of glutathione levels thus protecting against oxidative damage (26)