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Further studies confirmed that inhibition of the acidifier ion channel Ae2 or activation of the alkalization channel HVCn1 significantly improved T-cell function and the antitumor activity of Glypican 3 (GPC3)-specific CAR T cells in vitro 260

Regulation of skin cell behavior and extracellular matrix homeostasis Keratinocytes in the epidermis and fibroblasts in the dermis are the primary cell types responsible for synthesizing and degrading the extracellular matrix (ECM) in the skin

Genetic tools were previously used to express therapeutic proteins in Spirulina exogenously

The mTOR pathway is also modulated by AMPK