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HB might influence anabolic signaling by inhibiting the function of AMPK, an energy sensor that inhibits mTOR under low energy conditions

10.1186/s12958-021-00820-2 194 ZhaoY.PanS.LiY.WuX

Interestingly, prominent pimonidazole staining seemed to be concentrated in the retinal ganglion cell layer and inner nuclear layer of the retinal sections