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Since the inhibition of ASK1 (apoptosis signal-regulation kinase 1) in NLRP3 (NOD-like receptor thermal protein domain associated protein 3) mutant mice can reduce liver fibrosis, hepatocyte death, and liver TNF- expression, it suggests the application prospects of ASK1 inhibitor selonsertib in liver diseases

demonstrated that LC consumption considerably reduced the apoptotic cells located in seminiferous tubes [69]

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Our data demonstrate that APAP accumulates within flies, results in reactive oxygen species generation within the fat body, glutathione depletion, cell death, and mortality in a dose-dependent manner