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The IL-6/IL-6R signal promotes the formation of an immune-inflammatory microenvironment by inducing KP activation in pulmonary vascular cells (Cai et al., 2022)

Apr 15 2004;19(8):861-70

The CAT enzyme activity was evaluated from the decline in absorbance at 240 nm due to the loss of H 2 O 2

1A), alone and in combination with Telaglenastat (CB-839), a selective glutaminase inhibitor of both splice variants of glutaminase (KGA and GAC) with good oral bioavailability [63, 64], currently in phase II clinical trials (NCT04265534)