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Reis (B) et al., Effect of Early Treatment with Ivermectin among Patients with Covid-19, New England Journal of Medicine, doi:10.1056/NEJMoa2115869

Kaplan-Meier survival analysis revealed that the presence of the SBS4 signature was associated with significantly reduced SCLC survival outcomes (Log-rank test P = 0.003

Next, the apo-enzyme was eluted using GST elution buffer (50 mM Tris, 10 mM methylglutathione, pH 8) before relevant fractions were combined according to their A 280nm

The rapidly releasable pool is the maximum number of vesicles that can be released in 2 or 3 s and is thought to coincide with those vesicles that are docked to the active zone and primed for release