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Without a selective strategy targeting tumor cells, PS may directly interact with the DNA of normal cells, especially when they are concentrated in the cell nucleus

Neutrophils lacking epidermal growth factor receptor (EGFR) reduced anti-apoptotic myeloid cell leukemia 1 (MCL-1) levels and increased apoptosis, accelerating recovery from renal injury and diminishing subsequent fibrosis [57]

Accordingly, we made an evaluation of the relationships between the ferroptosis-associated genes and TNM stage, tumor grade, histological type, primary therapy outcome, invasion and recurrence of tumor, and accessing the different prognosis molecular typing based on ferroptosis-associated genes