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See Sikiric et al., Curr Pharm Des, 2018 (PMID:30246642) for an overview of the reported mechanisms, and Chang et al., J Appl Physiol, 2011 (PMID:21030673) for a representative tendon-fibroblast study

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(2020) indicates that injectable fillers like hyaluronic acid and polylactic acid for penile augmentation can yield significant improvements in size and help reduce psychological distress, with no serious adverse events reported