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After vial has been opened: Store opened (in-use) vial in the original carton in the refrigerator at 36F to 46F (2C to 8C) or at room temperature [up to 86F (30C)]

[9] The most frequently observed adverse reactions are mild injection-site pain, transient erythema, and localized warmth, typically resolving within minutes

In the first enzyme reaction, methylcobalamin is used to recycle the folate cofactor 5-methyltetrahydrofolate to tetrahydrofolate thereby allowing the folate cofactor to participate in a cycle involving the biosynthesis of purines and pyrimidines

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