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Pyocyanin in the impairment of wound healing Pseudomonas aeruginosa has been reported to impair natural repair processes, thus impeding the efficiency of healing mechanisms, especially the restoration of epithelial integrity, after injuries, burns, and wounds (Ruffin and Brochiero 2019)

The same study found a 20% reduction in intestinal weight and a significant thinning of the microvillus membrane Thiamine injected into acupoints successfully prevented intestinal permeability among colon cancer patients in one Chinese report

Inhibiting myofibroblast ECM secretion and contraction, as well as fibroblast-to-myofibroblast transformation (FMT), is a pivotal therapeutic approach for organ fibrosis (Hinz and Lagares, 2020

3.7.1 Immunomodulation and barrier reinforcement A fundamental mechanism shared by Lactobacillus and Bifidobacterium species involves the modulation of host immunity through cytokine regulation ( Table 2 )