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M2 Macrophages Induced by Prostaglandin E2and IL-6 from Cervical Carcinoma Are Switched to Activated M1 Macrophages by CD4+Th1 Cells

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KPV is small enough at just 342 daltons to be recognized and transported directly into the cell via PepT1.2 This matters clinically for one specific reason: PepT1 expression is significantly upregulated in inflamed intestinal tissue.2 The more inflamed the gut, the more actively it imports KPV