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doi: 10.1186/1472-6882-9-53 CrossRef Google Scholar View reference in article 39 FruscalzoA.SalmeriM

Mechanistically, microbial dysbiosis exacerbates renal injury and fibrosis by increasing intestinal permeability, disrupting lipid metabolism, inducing ROS-mediated oxidative stress, and activating TLR4-mediated inflammatory responses ( Figure 4 ) [128]