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Nobiletin induces ferroptosis in human skin melanoma cells through the GSK3-mediated Keap1/Nrf2/HO-1 signalling pathway

DISEASES OF THE CIRCULATORY SYSTEM (I42.9 I60.7) 4th I45.6 Pre-excitation syndrome Accelerated atrioventricular conduction Accessory atrioventricular conduction Anomalous atrioventricular excitation Lown-Ganong-Levine syndrome Pre-excitation atrioventricular conduction Wolff-Parkinson-White syndrome I45.8 Other specified conduction disorders I45.81 Long QT syndrome 5th I51 COMPLICATIONS AND ILL-DEFINED DESCRIPTIONS OF HEART DISEASE 4th Excludes1: any condition in I51.4 I51.9 due to hypertension (I11.-) any condition in I51.4 I51.9 due to hypertension and CKD (I13.-) heart disease specified as rheumatic (I00 I09) I51.7 Cardiomegaly Cardiac dilatation Cardiac hypertrophy Ventricular dilatation I45.9 Conduction disorder, unspecified Heart block NOS Stokes-Adams syndrome I46 CARDIAC ARREST 4th Excludes1: cardiogenic shock (R57.0) I46.2 Cardiac arrest due to underlying cardiac condition Code first underlying cardiac condition I46.8 Cardiac arrest due to other underlying condition Code first underlying condition I46.9 Cardiac arrest, cause unspecified I47 PAROXYSMAL TACHYCARDIA 4th Code first tachycardia complicating: abortion or ectopic or molar pregnancy (O00 O07, O08.8) obstetric surgery and procedures (O75.4) Excludes1: tachycardia NOS (R00.0) sinoauricular tachycardia NOS (R00.0) sinus [sinusal] tachycardia NOS (R00.0) I47.1 Supraventricular tachycardia Atrial (paroxysmal) tachycardia Atrioventricular [AV] (paroxysmal) tachycardia Atrioventricular re-entrant (nodal) tachycardia [AVNRT] [AVRT] Junctional (paroxysmal) tachycardia Nodal (paroxysmal) tachycardia I49 OTHER CARDIAC ARRHYTHMIAS 4th Code first cardiac arrhythmia complicating: abortion or ectopic or molar pregnancy (O00 O07, O08.8) obstetric surgery and procedures (O75.4) Excludes1: neonatal dysrhythmia (P29.1-) sinoatrial bradycardia (R00.1) sinus bradycardia (R00.1) vagal bradycardia (R00.1) Excludes2: bradycardia NOS (R00.1) I49.0 Ventricular fibrillation and flutter I49.01 Ventricular fibrillation 5th I49.02 Ventricular flutter I49.1 Atrial premature depolarization Atrial premature beats I49.5 Sick sinus syndrome Tachycardia-bradycardia syndrome I49.9 Cardiac arrhythmia, unspecified Arrhythmia (cardiac) NOS I50 HEART FAILURE 4th 4th Code first: heart failure complicating abortion or ectopic or molar pregnancy (O00 O07, O08.8) heart failure due to hypertension (I11.0) heart failure due to hypertension with CKD (I13.-) 5th 200 ICD_10-4th_ed.indb 200 6th 7th Additional Character Required (I00 I99) 3-character code (I60 I69) CEREBROVASCULAR DISEASES Use additional code to identify presence of: alcohol abuse and dependence (F10.-) exposure to environmental tobacco smoke (Z77.22) history of tobacco dependence (Z87.891) hypertension (I10 I16) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) Excludes1: traumatic intracranial hemorrhage (S06.-) I60 NONTRAUMATIC SUBARACHNOID HEMORRHAGE 4th Excludes1: syphilitic ruptured cerebral aneurysm (A52.05) Excludes2: sequelae of subarachnoid hemorrhage (I69.0-) I60.0 Nontraumatic subarachnoid hemorrhage from

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A., Kupfer, H., Sciaky, N