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These are the glue that keeps the gut lining and vascular barriers intact, which is why it is often cited in discussions regarding leaky gut and systemic inflammation

Multiple studies have reported that Epithalon administration can extend both mean and maximum lifespan by 10-25% or more compared to control animals - effects approaching those seen with caloric restriction

For example, PRMT1-mediated STAT6 methylation, induced by hypoxia-inducible factor (HIF)-1, promoted M2 macrophage polarization, contributing to fibrotic signaling in lung epithelial cells [91]

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