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When layered together, the acidic environment created by AHAs can destabilise retinol before it converts properly, essentially neutralising its effectiveness whilst potentially increasing irritation

Imaging of assembloids and thin tissue sections was performed using an inverted multiphoton laser-scanning microscope (Zeiss LSM 780 NLO)

This is further supported by studies (147), which identified deficits in nNOS neurons in various enteric neuropathies, including those associated with IBD

Gene-specific primers (Table S4) were used to amplify the target sequence with these cycles: first denaturation step for 2 min at 95 C, at least 15 cycles with 30 s at 95 C, annealing at 70 C for 1 min with a decreasing rate of 1 C/cycle until the melting temperature (T m