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reliable systemic delivery Subcutaneous injection Investigated in some metabolic studies and currently used in research settings Intra-articular injection Applied in osteoarthritis models for localized cartilage regeneration effects Common Model Organisms AOD-9604 has been studied across multiple species for various research applications: Mice ob/ob and beta-3-AR knockout strains

A repeated-measures two-way ANOVA revealed a significant main effect of the factors treatment (F (1,16) = 12.47, P = 0.0028), time (days) (F (5,80) = 4.437, P = 0.0012), and a significant treatment time interaction (F (5,80) = 10.89, P 0.05