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These factors orchestrate a transcriptional network that coordinates the expression of nuclear genes involved in mtDNA transcription, respiratory chain assembly, and mitochondrial dynamics

Certain cyclooxygenase (COX) enzymes, necessary for LPO, have been localized within LDs and shown to enhance angiogenesis, suggesting that elevated LD levels may play a critical role in ferroptosis resistance (72)

Abstract Emerging research underscores the pivotal role of the gutimmunebrain axis, a dynamic bidirectional communication system involving intricate interactions between the gut microbiota, immune responses, and the central nervous system